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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
37.88
Human Site:
Y113
Identified Species:
55.56
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
Y113
L
I
Q
D
A
P
N
Y
G
W
E
V
A
Q
P
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
K94
N
V
G
C
I
P
K
K
L
M
H
Q
A
A
L
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
Y113
L
I
Q
D
A
P
H
Y
G
W
E
V
A
Q
P
Dog
Lupus familis
XP_850181
509
55065
Y100
M
I
R
D
A
P
H
Y
G
W
D
V
A
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
Y113
M
I
R
D
A
H
H
Y
G
W
E
V
A
Q
P
Rat
Rattus norvegicus
Q9Z0J5
526
56406
Y115
M
I
R
D
A
Q
H
Y
G
W
E
V
A
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
Y103
A
L
K
D
A
Q
H
Y
G
W
S
V
A
H
P
Frog
Xenopus laevis
NP_001080052
504
54666
Y93
T
M
K
D
A
P
H
Y
G
W
G
T
P
Y
E
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
F189
A
M
E
D
A
R
K
F
G
W
E
F
A
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
Y189
A
V
H
E
A
A
A
Y
G
W
N
V
D
E
K
Honey Bee
Apis mellifera
NP_001171496
537
59227
Y127
S
I
H
D
S
V
S
Y
G
W
Q
L
P
D
P
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
Y246
S
I
H
D
A
K
K
Y
G
W
K
L
P
E
G
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
Y84
S
M
H
D
A
K
H
Y
G
W
Q
V
P
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
Y100
E
L
E
D
A
K
N
Y
G
W
E
I
N
E
K
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
H84
D
L
A
T
R
V
S
H
A
N
E
Y
G
L
Y
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
F83
S
V
E
Q
T
A
P
F
D
W
P
T
F
K
Q
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
13.3
93.3
73.3
N.A.
73.3
73.3
N.A.
N.A.
53.3
40
40
N.A.
33.3
40
40
40
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
60
66.6
N.A.
53.3
66.6
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
46.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
7
0
75
13
7
0
7
0
0
0
50
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
75
0
0
0
0
7
0
7
0
7
13
7
% D
% Glu:
7
0
19
7
0
0
0
0
0
0
44
0
0
25
7
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
7
7
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
82
0
7
0
7
0
7
% G
% His:
0
0
25
0
0
7
44
7
0
0
7
0
0
7
0
% H
% Ile:
0
44
0
0
7
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
13
0
0
19
19
7
0
0
7
0
0
7
13
% K
% Leu:
13
19
0
0
0
0
0
0
7
0
0
13
0
7
7
% L
% Met:
19
19
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
13
0
0
7
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
32
7
0
0
0
7
0
25
0
44
% P
% Gln:
0
0
13
7
0
13
0
0
0
0
13
7
0
32
13
% Q
% Arg:
0
0
19
0
7
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
25
0
0
0
7
0
13
0
0
0
7
0
0
0
0
% S
% Thr:
7
0
0
7
7
0
0
0
0
0
0
13
0
0
0
% T
% Val:
0
19
0
0
0
13
0
0
0
0
0
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
88
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
7
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _